Basal cell carcinoma (BCC) is the most common form of skin cancer, affecting approximately one million Americans each year. These cancers arise in the basal cells, which line the deepest layer of the epidermis (top skin layer). Basal cell carcinomas are rarely fatal, but can be highly disfiguring.
Squamous cell carcinoma (SCC) arises in the squamous cells that make up most of the skin’s upper layers (epidermis). Squamous cell carcinomas may occur on all areas of the body including the mucous membranes and genitals, but are most common in areas frequently exposed to the sun, such as the rim of the ear, lower lip, face, bald scalp, neck, hands, arms and legs.
Melanoma is a malignant tumor that originates in melanocytes, cells which produce the pigment melanin that colors our skin, hair, and eyes. The majority of melanomas are black or brown. However, some melanomas are skin-colored, pink, red, purple, blue or white. Melanoma is the most serious form of skin cancer. However, if it is recognized and treated early, it is nearly 100 percent curable. But if it is not, the cancer can advance and spread to other parts of the body, where it becomes hard to treat and can be fatal. While it is not the most common of the skin cancers, it causes the most deaths.
1. As a postal carrier, I have had numerous bouts with skin cancer. I have used FRANKINCENSE on each “mole” morning and night for a week, and they disappear. I’ve had some come back, which is to be expected since I spend so much time outdoors, but Frankincense always works and works quickly.
2. My father-in-law had a mole on his forehead that looked worrisome. He applied FRANKINCENSE directly on the spot (undiluted) twice daily, and whatever it was, it just fell off. The skin underneath was completely normal, and there is not a sign that it was ever there.
3. I had what I self-diagnosed as Melanoma on my forehead (based on photos I compared with online), and I applied FRANKINCENSE undiluted on it daily. It took several months to disappear, but now there is no size of it, and it has not come back.
4. I had several spots on my face that were diagnosed as Melanoma. The MD wanted to do surgery, but I opted to try essential oils. I didn’t have Frankincense, which is commonly used for skin cancer, but used PLAGUE DEFENSE instead. Essential oils only kill bad cells and leaves the good ones. My spots initially turned red and then scabbed over. Skin cancer is funnel shaped, so each time the scab fell off, the spot got smaller. It seems like it works it’s way to the very root of it. When they were finally gone, I had no scars and couldn’t detect where the cancer had been. Wow!
5. I spent many years lying in the sun on the beach, and at the age of 40 began seeing an uneven mole-like spot appear on my forehead. My MD diagnosed it as basil cell carcinoma. I put off surgery so I could first try essential oils, and FRANKINCENSE applied morning and night completely took care of it in less than 2 weeks. Yipeeee!!!! Not only did I save $$, but I also felt no pain and have no scar.
6. Dr. John L. Robertson, a professor in the Virginia-Maryland Regional College of Veterinary Medicine at Virginia Tech and director of the college’s Center for Comparative Oncology, has worked with the use of FRANKINCENSE essential oil as a possible treatment for malignant melanoma in horses, noting that the risk factors for malignant melanoma in people and horses are very similar. Robertson’s research showed that equine melanomas respond to this therapy. This article follows below.
7. I used FRANKINCENSE on a precancerous spot, and it flaked off. Thanks. - Roberta
8. I have read about people putting iodine on all types of skin cancers, growths, and so on to get rid of them. I had a small growth on the back of my hand, so I started putting cheap old tincture of iodine on it. It was totally gone in 2 weeks and left just a small scar. - Kay
Boswellic acid acetate induces differentiation and apoptosis in highly metastatic melanoma and fibrosarcoma cells
Zhao W, Entschladen F, Liu H, Niggemann B, Fang Q, Zaenker KS, Han R.
Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, No1 Xiannong Tan Street, Beijing 100050, China. wanzhou.zhao@Roswellpark.org
The aim of the study was to investigate the antitumor and/or preventive effect of BC-4, an isomeric compound isolated from the plant Boswellia carteri Birdw. containing alpha- and beta-boswellic acid acetate in 1:1, MW 498.3. We used the MTT (3-(4,5-dimethylthiazol-2-yl) 2,5-diphenyltetrazolium bromide) assay to study the growth inhibition activity of BC-4. Tumor cells migration within a three-dimensional collagen matrix was recorded by time-lapse videomicroscopy and computer-assisted cell tracking. Topoisomerase II was isolated from mouse melanoma B16F10 cells and its activity was determined by its ability to cut plasmid pBR322 DNA. The secretion and activity of matrix metalloproteinases (MMPs) from human fibrosarcoma HT-1080 cells were determined by gelatin zymography. BC-4 was a cytostatic compound and could induce the differentiation of B16F10 mouse melanoma cells, blocked the cell population in G1 phase and inhibited topoisomerase II activity. The G1 phase population of B16F10 cells was increased from 57.4 to 87.7%, while S phase population was reduced from 33.3 to 5.9% after treatment with BC-4 at 25 microM concentration for 48 h. BC-4 also inhibited the migration activity of B16F10. BC-4 could induce apoptosis of HT-1080 cells, as proved by acridine orange fluorescence staining, Wright-Giemsa staining, electromicroscopy, DNA fragmentation and flow cytometry. BC-4 inhibited the secretion of MMPs from HT-1080 cells, too. In conclusion, if it turns out that BC-4 is a well tolerated substance, exhibiting no significant toxicity or side effects, being evaluated currently in China, BC-4 is a good candidate for the prevention of primary tumor, invasion and metastasis. Copyright 2002 International Society for Preventive Oncology
PMID: 12600419 [PubMed - indexed for MEDLINE]
Virginia Tech Researcher Examining Malignant Melanoma in Horses
Malignant melanoma is a dangerous, aggressive form of cancer and approximately 54,000 new cases are diagnosed every year, according to the American Cancer Society. Interestingly, there are many similarities between malignant melanoma in horses and malignant melanoma in people.
Recognizing the extraordinary opportunity for translational research that the disease represents, Dr. John L. Robertson, a professor in the Virginia-Maryland Regional College of Veterinary Medicine at Virginia Tech and director of the college's Center for Comparative Oncology (CECO), has been looking at one experimental treatment.
During a presentation before a regional meeting of the American Cancer Society in Roanoke, Va., Robertson detailed some of the work he is doing with the use of Frankincense oil as a possible treatment for malignant melanoma in horses.
The risk factors for malignant melanoma in people and horses are very similar, according to Robertson. In people, risk factors include pale complexion and hair, exposure to excessive sunlight and sunburns and aging. Horses at risk also have a pale coat of grey to white and there seems to be a correlation to aging, which could be a result of chronic exposure to sunlight, he said. In each, the disease is an infiltrated pigmented malignancy that is difficult to manage. Conventional therapies include chemotherapy, radiation, immunotherapy, and surgery. The disease often affects horses with the development of lesions on the lips, neck, and perineal area.
Robertson presented the story of Chili, a handsome, 11-year old Thoroughbred and champion jumper that was diagnosed with multi-centric malignant melanoma at the age of seven. Told by her local practitioner that there was not much that could be done for Chili and aware of Robertson's interest in evaluating an experimental therapy, Chili's owner asked if Robertson would work with Chili.
That experimental therapy involved the use of Frankincense oil, a compound known as a valuable treatment for wounds for more than 2,000 years, and one people are reminded of every Christmas when they recall the Gifts of the Magi brought to the Christ-child.
Frankincense oil is a fragrant botanical oil distillate made from fermented plants, explains Robertson, who adds that it contains hundreds of constituents, including boswellic acid, a component that is known to have anti-neoplastic properties. Scientists have demonstrated that the oil has potent anti-inflammatory effects and anti-tumor properties when evaluated in tissue culture with tumors such as astrocytomas, melanomas, and fibrosarcomas. Furthermore, he said, it appears to have fairly selective anti-tumor activity and does not appear to disrupt normal cells. But much about how it affects actual cancer patients is unknown.
Chili's experimental protocol involved daily injections of medicinal grade, sterile frankincense oil directly into his tumors and the application of oil on topical tumors, while Chili's comfort and well-being was carefully maintained through pain and nutritional management, including copious amounts of his favorite peeled baby carrots and peppermints.
The lesions were observed, measured, photographed, and periodically biopsied, according to Robertson. Those tumor biopsies demonstrated that some small tumor cells were destroyed by the treatment and those treated topically were reduced in size. Unfortunately, however, Chili passed away on October 18, 2005 as a result of the progressive and relentless growth of the non-treated tumors.
Chili's involvement with CeCO and the experimental protocol did result in some important achievements, according to Robertson.
"I think this research on Frankincense oil suggests that this ancient medicine may have significant modern uses for chemotherapy of non-resectable malignancies," said Robertson, a professor in the Department of Biomedical Sciences and Pathobiology. "This research showed that equine melanomas respond to this therapy."
Information gleaned from this Phase I-II National Cancer Institute format clinical trial has supported the development of grant applications and helped in the treatment of five additional horses, Robertson said. A collaboration with the Clinical Research Program at Wake Forest University's Comprehensive Cancer Center is being discussed.
Frankincense and Cancer Prevention
Frankincense (Boswellia carteri) may be a good candidate for prevention of cancer and cancer metastasis. A study done by Zhao et al. (2003) published in Cancer Detection and Prevention found that a substance called BC-4, an isomeric compound isolated from Boswellia carteri, may reduce cancerous cell production and metastasis (spread of cancerous cells from one part of the body to another).
Lemon Grass vs. Cancer Cells
Fresh lemon grass fields in Israel become mecca for cancer patients
By Allison Kaplan Sommer - April 02, 2006
At first, Benny Zabidov, an Israeli agriculturalist who grows greenhouses full of lush spices on a pastoral farm in Kfar Yedidya in the Sharon region, couldn't understand why so many cancer patients from around the country were showing up on his doorstep asking for fresh lemon grass. It turned out that their doctors had sent them.
"They had been told to drink eight glasses of hot water with fresh lemon grass steeped in it on the days that they went for their radiation and chemotherapy treatments," Zabidov told ISRAEL21c. "And this is the place you go to in Israel for fresh lemon grass."
It all began when researchers at Ben Gurion University of the Negev discovered last year that the lemon aroma in herbs like lemon grass kills cancer cells in vitro, while leaving healthy cells unharmed.
The research team was led by Dr. Rivka Ofir and Prof. Yakov Weinstein, incumbent of the Albert Katz Chair in Cell-Differentiation and Malignant Diseases, from the Department of Microbiology and Immunology at BGU.
Citral is the key component that gives the lemony aroma and taste in several herbal plants such as lemon grass (Cymbopogon citratus), melissa (Melissa officinalis) and verbena (Verbena officinalis.)
According to Ofir, the study found that citral causes cancer cells to "commit suicide: using apoptosis, a mechanism called programmed cell death." A drink with as little as one gram of lemon grass contains enough citral to prompt the cancer cells to commit suicide in the test tube.
The BGU investigators checked the influence of the citral on cancerous cells by adding them to both cancerous cells and normal cells that were grown in a petri dish. The quantity added in the concentrate was equivalent to the amount contained in a cup of regular tea using one gram of lemon herbs in hot water. While the citral killed the cancerous cells, the normal cells remained unharmed.
The findings were published in the scientific journal Planta Medica, which highlights research on alternative and herbal remedies. Shortly afterwards, the discovery was featured in the popular Israeli press.
Why does it work? Nobody knows for certain, but the BGU scientists have a theory.
"In each cell in our body, there is a genetic program which causes programmed cell death. When something goes wrong, the cells divide with no control and become cancer cells. In normal cells, when the cell discovers that the control system is not operating correctly - for example, when it recognizes that a cell contains faulty genetic material following cell division - it triggers cell death," explains Weinstein. "This research may explain the medical benefit of these herbs."
The success of their research led them to the conclusion that herbs containing citral may be consumed as a preventative measure against certain cancerous cells.
As they learned of the BGU findings in the press, many physicians in Israel began to believe that while the research certainly needed to be explored further, in the meantime it would be advisable for their patients, who were looking for any possible tool to fight their condition, to try to harness the cancer-destroying properties of
That's why Zabidov's farm - the only major grower of fresh lemon grass in Israel - has become a pilgrimage destination for these patients. Luckily, they found themselves in sympathetic hands. Zabidov greets visitors with a large kettle of aromatic lemon grass tea, a plate of cookies, and a supportive attitude.
"My father died of cancer, and my wife's sister died young because of cancer," said Zabidov. "So I understand what they are dealing with. And I may not know anything about medicine, but I'm a good listener. And so they tell me about their expensive painful treatments and what they've been through. I would never tell them to stop being treated, but it's great that they are exploring alternatives and drinking the lemon grass tea as well."
Zabidov knew from a young age that agriculture was his calling. At age 14, he enrolled in the Kfar Hayarok Agricultural high school. After his army service, he joined an idealistic group which headed south, in the Arava desert region, to found a new moshav (agricultural settlement) called Tsofar.
"We were very successful; we raised fruits and vegetables, and," he notes with a smile, "We raised some very nice children."
On a trip to Europe in the mid-80s, he began to become interested in herbs. Israel, at the time, was nothing like the trend-conscious cuisine-oriented country it is today, and the only spices being grown commercially were basics like parsley, dill, and coriander.
Wandering in the Paris market, looking at the variety of herbs and spices, Zabidov realized that there was a great export potential in this niche. He brought samples back home with him, "which was technically illegal," he says with a guilty smile, to see how they would grow in his desert greenhouses. Soon, he was growing basil,
oregano, tarragon, chives, sage, marjoram and melissa, and mint just to name a few.
His business began to outgrow his desert facilities, and so he decided to move north, settling in the moshav of Kfar Yedidya, an hour and a half north of Tel Aviv. He is now selling "several hundred kilos" of lemon grass per week, and has signed with a distributor to package and put it in health food stores.
Zabidov has taken it upon himself to learn more about the properties of citral, and help his customers learn more, and has invited medical experts to his farm to give lectures about how the citral works and why.
He also felt a responsibility to know what to tell his customers about its use. "When I realized what was happening, I picked up the phone and called Dr. Weinstein at Ben-Gurion University, because these people were asking me exactly the best way to consume the citral. He said to put the loose grass in hot water, and drink about eight glasses each day."
Zabidov is pleased by the findings, not simply because it means business for his farm, but because it might influence his own health.
Even before the news of its because were demonstrated, he and his family had been drinking lemon grass in hot water for years, "just because it tastes good." A drink with as little as one gram of lemon grass contains enough citral to prompt cancer cells to commit suicide in the test tube.
This service is provided by ISRAEL21c http://www.israel21c.org
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